免疫原Human recombinant protein fragment corresponding to amino acids 21-153 of human IL2 (NP_000577) produced in E.coli.
基因ID3558 (Human);
蛋白编码P60568
同义词IL-2; lymphokine; TCGF
宿主物种Mouse
抗体分型IgG2a
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
推荐稀释比WB 1:2000< br/>IHC 1:150
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
