免疫原Full length human recombinant protein of human LDHA (NP_005557) produced in HEK293T cell.
基因ID(Human); 3939 (Mouse); 16828
蛋白编码P00338,
同义词GSD11; HEL-S-133P; LDHM; PIG19
宿主物种Mouse
抗体分型IgG1
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84-89% sequence similarities and 69-75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers. Mutations in the LDHA gene can lead to Glycogen storage disease 11 (GSD11).
推荐稀释比WB 1:1000< br/>IHC 1:50< br/>IP 2ug:500ul
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
