Sprouty 2 Rabbit mAb

货号:R05517

货期：

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应用WB,IHC-P,IF-ICC
反应物种Human,Rat
理论分子量35kDa
表观分子量35kDa
免疫原A synthetic peptide of human SPRY2
基因ID10253
蛋白编码O43597
同义词hSPRY2; Sprouty2; SPRY2;
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2 (By similarity). Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis (By similarity). Inhibits TGFB- induced epithelial-to-mesenchymal transition in retinal lens epithelial cells (By similarity). Inhibits CBL/C-CBL-mediated EGFR ubiquitination (PubMed:17974561).
推荐稀释比WB 1:1000-1:5000
IHC-P/IF-P 1:50
IF-ICC 1:100
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.