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Rabbit Monoclonal Antibody
兔单克隆抗体
Lin28B Rabbit mAb

货号:R05718

  • 规格价格
  • 100 μL 1800
  • 50 μL 1000
货期:
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  • 应用WB,IF-ICC,FCM,IP
  • 反应物种Human
  • 理论分子量32kDa
  • 表观分子量27kDa
  • 免疫原A synthetic peptide of human LIN28B
  • 基因ID389421
  • 蛋白编码Q6ZN17
  • 同义词CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B;
  • 宿主物种Rabbit
  • 抗体分型IgG
  • 纯化Affinity purification
  • 储存Store at -20℃. Avoid freeze / thaw cycles.
  • 靶点背景The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.
  • 推荐稀释比WB 1:1000
    IF-ICC 1:200
    FCM 1:20
    IP 1:20
  • 产品形式Liquid
  • Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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